Eddie Brock attempts to reignite his career by interviewing serial killer Cletus Kasady, who becomes the host of the symbiote Carnage and escapes prison after a failed execution.
A failed reporter is bonded to an alien entity, one of many symbiotes who have invaded Earth. But the being takes a liking to Earth and decides to protect it.
Cassandra Webb is a New York metropolis paramedic who begins to demonstrate signs of clairvoyance. Forced to challenge revelations about her past, she needs to safeguard three young women from a deadly adversary who wants them destroyed.