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- A simple man, Dr. Walter Newman, has high aspirations to cure all disease through genetic manipulation. His obsession with his mission draws him deeper into his own dark world, distracting him from his wife Olivia and from his responsibilities to his patients at the Edgewood Asylum. The doctors loyal but diabolical nurse, Ms. Tinsley, decides to take matters into her own hands and in secret she conducts her own experiment. When Dr. Newman realizes what has been done, a deformed creature that defies nature is created. Part human, part nightmare. Dr. Newman knows what he must do, but is it already too late?
- A young, beautiful couple hold their wedding at an old farm, despite warnings of a mutated West Nile Virus outbreak nearby. Their special day is ruined when the virus spreads and the wedding guests begin transforming into unstoppable, murderous maniacs. Now the couple must fight their way to safety while avoiding certain death at the hands of hundreds of infected killers.
- Catapulted into a world of astral projections, a young woman traverses time and space, often to unexpected destinations, including the crime scenes of a deranged killer. Little does she know, the killer is also an astral projector, setting the stage for a chilling confrontation that blurs the boundaries of reality and the paranormal.
- Two foster girls find themselves in an estranged murder plot, with a rich girl who is has no idea of their terrifying past.