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- DirectorFelix van GroeningenStarsSteve CarellMaura TierneyJack Dylan GrazerBased on the best-selling pair of memoirs from father and son David and Nic Sheff, Beautiful Boy chronicles the heartbreaking and inspiring experience of survival, relapse and recovery in a family coping with addiction over many years.
- DirectorJerry SchatzbergStarsAl PacinoKitty WinnAlan VintFollows the lives of heroin addicts who frequent "Needle Park" in New York City.
- DirectorUli EdelStarsNatja BrunckhorstEberhard AurigaPeggy BussieckA teen girl in 1970s Berlin becomes addicted to heroin. Everything in her life slowly begins to distort and disappear as she befriends a small crew of junkies and falls in love with a drug-abusing male prostitute.
- DirectorTerry GilliamStarsJohnny DeppBenicio Del ToroTobey MaguireAn oddball journalist and his psychopathic lawyer travel to Las Vegas for a series of psychedelic escapades.
- DirectorJoseph CasteloStarsThomas MannLucy FryLogan HuffmanA student at a private school uses his connections to establish a drug trafficking network there.
- DirectorJonas ÅkerlundStarsJason SchwartzmanJohn LeguizamoPatrick FugitA drug dealer introduces one of his customers, a 'speed freak', to the man who runs the meth lab. A crazy three-day adventure ensues.
- DirectorBenny SafdieJosh SafdieStarsArielle HolmesCaleb Landry JonesBuddy DuressA young woman struggles to reconcile her love for her boyfriend and for heroin, as she finds out that suicide is the only way for her boyfriend to forgive her for her misdeed.
- DirectorJon S. BairdStarsJames McAvoyJamie BellEddie MarsanA corrupt, junkie cop with bipolar disorder attempts to manipulate his way through a promotion in order to win back his wife and daughter while also fighting his own inner demons.
- DirectorDarren AronofskyStarsEllen BurstynJared LetoJennifer ConnellyThe drug-induced utopias of four Coney Island people are shattered when their addictions run deep..
- DirectorD.J. CarusoStarsVal KilmerVincent D'OnofrioAdam GoldbergAfter a tragic incident, a man drifts into a world populated by thugs and speed junkies.
- DirectorCollin SchiffliStarsDavid DastmalchianKim ShawJohn HeardJude and Bobbie are conning their way through life to feed their endless addiction. When confronted with the reality of their situation, the young lovers must decide if true love can prevail in the face of all else.
- DirectorNathan FrankowskiStarsKat DenningsChad Michael MurrayRupert FriendA drama centered around Renee Yohe and her battle with drugs, depression, and other life issues that ultimately leads to the founding of charity group To Write Love on Her Arms.
- DirectorErik SkjoldbjærgStarsChristina RicciJonathan Rhys MeyersJessica LangeA young woman struggles with depression during her first year at Harvard.
- DirectorMartin ScorseseStarsLeonardo DiCaprioJonah HillMargot RobbieBased on the true story of Jordan Belfort, from his rise to a wealthy stock-broker living the high life to his fall involving crime, corruption and the federal government.
- DirectorJoachim TrierStarsAnders Danielsen LieHans Olav BrennerIngrid OlavaOne day in the life of Anders, a young recovering drug addict, who takes a brief leave from his treatment center to interview for a job and catch up with old friends in Oslo.
- DirectorNeil ArmfieldStarsHeath LedgerAbbie CornishGeoffrey RushA poet falls in love with an art student who gravitates to his bohemian lifestyle -- and his love of heroin. Hooked as much on one another as they are on the drug, their relationship alternates between states of oblivion, self-destruction, and despair.
- DirectorMarielle HellerStarsBel PowleyAlexander SkarsgårdKristen WiigA teen artist living in 1970s San Francisco enters into an affair with her mother's boyfriend.
- DirectorDanny BoyleStarsEwan McGregorEwen BremnerJonny Lee MillerRenton, deeply immersed in the Edinburgh drug scene, tries to clean up and get out despite the allure of drugs and the influence of friends.
- DirectorGregg ArakiStarsAnna FarisJohn KrasinskiAdam BrodyAfter a young actress unknowingly eats her roommate's marijuana cupcakes, her day becomes a series of misadventures.
- DirectorGus Van SantStarsMatt DillonKelly LynchJames Le GrosA pharmacy-robbing dope fiend and his crew pop pills and evade the law.
- DirectorTed DemmeStarsJohnny DeppPenélope CruzFranka PotenteThe story of how George Jung, along with the Medellín Cartel headed by Pablo Escobar, established the American cocaine market in the 1970s in the United States.
- DirectorMonty LapicaStarsMonty LapicaDiane VenoraMichael BowenA pill-popping mom has her drug-abusing teen son abducted into a private intervention facility that means well.
- DirectorScott KalvertStarsLeonardo DiCaprioLorraine BraccoMarilyn SokolA teenager finds his dreams of becoming a basketball star threatened after he free falls into the harrowing world of drug addiction.
- DirectorMarek KanievskaStarsAndrew McCarthyJami GertzRobert Downey Jr.A college freshman returns to L.A. for the holidays at his ex-girlfriend's request, but discovers that his former best friend has an out-of-control drug habit.
- DirectorFloyd MutruxStarsClifton Tip FredellKit RyderBilly GrayA "straight" couple dabbles in drugs and become heroin addicts.