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- CreatorChuck LorreBill PradyStarsJohnny GaleckiJim ParsonsKaley CuocoAspiring film actress Penny moves into a Pasadena apartment across the hall from brilliant, but socially awkward, physicists Sheldon Cooper and Leonard Hofstadter and shows them how little they know about life outside of the lab.
- CreatorCarter BaysCraig ThomasStarsJosh RadnorJason SegelCobie SmuldersA father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
- CreatorAaron KorshStarsGabriel MachtPatrick J. AdamsMeghan MarkleOn the run from a drug deal gone bad, brilliant college dropout Mike Ross finds himself working with Harvey Specter, one of New York City's best lawyers.
- CreatorLee AronsohnChuck LorreStarsJon CryerAshton KutcherAngus T. JonesA hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.
- CreatorSteven LevitanChristopher LloydStarsEd O'NeillSofía VergaraJulie BowenThree different, but related, families face trials and tribulations in their own uniquely comedic ways.
- CreatorSeth MacFarlaneDavid ZuckermanStarsSeth MacFarlaneAlex BorsteinSeth GreenIn a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- CreatorRob McElhenneyGlenn HowertonStarsCharlie DayGlenn HowertonRob McElhenneyFive friends with big egos and small brains are the proprietors of an Irish pub in Philadelphia.
- CreatorElizabeth MeriwetherStarsZooey DeschanelJake JohnsonMax GreenfieldAfter a bad break-up, Jess, an offbeat young woman, moves into an apartment loft with three single men. Although they find her behavior very unusual, the men support her - most of the time.
- CreatorDavid CraneMarta KauffmanStarsJennifer AnistonCourteney CoxLisa KudrowFollows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- CreatorHart HansonStarsEmily DeschanelDavid BoreanazMichaela ConlinF.B.I. Special Agent Seeley Booth teams up with the Jeffersonian's top anthropologist, Dr. Temperance Brennan, to investigate cases where all that's left of the victims are their bones.
- CreatorTom KapinosStarsDavid DuchovnyNatascha McElhoneEvan HandlerA writer tries to juggle his career, his relationship with his daughter and his ex-girlfriend, as well as his appetite for beautiful women.
- CreatorMark BrazillBonnie TurnerTerry TurnerStarsTopher GraceLaura PreponMila KunisA comedy revolving around a group of teenage friends, their mishaps, and their coming of age, set in 1970s Wisconsin.
- CreatorShana Goldberg-MeehanScott SilveriStarsMatt LeBlancPaulo CostanzoDrea de MatteoIn this spin-off of Friends (1994), Joey Tribbiani moves to Los Angeles to pursue his acting career.
- CreatorDoug EllinStarsKevin ConnollyAdrian GrenierKevin DillonFilm star, Vince Chase, navigates the vapid terrain of Los Angeles with a close circle of friends and his trusty agent.
- CreatorDan HarmonStarsJoel McHaleDanny PudiDonald GloverA suspended lawyer is forced to enroll in a community college with an eccentric staff and student body.
- CreatorNeal BrennanDave ChappelleStarsDave ChappelleDonnell RawlingsRudy RushComedian Dave Chappelle hosts this sketch-comedy show that parodies many of the nuances of race and culture.
- CreatorAndy BorowitzSusan BorowitzStarsWill SmithJames AveryAlfonso RibeiroA streetwise, poor young man from Philadelphia is sent by his mother to live with his aunt, uncle and cousins in their Bel-Air mansion.
- CreatorWhitney CummingsMichael Patrick KingStarsKat DenningsBeth BehrsGarrett MorrisTwo young women waitressing at a greasy spoon diner strike up an unlikely friendship in the hopes of launching a successful business - if only they can raise the cash.
- CreatorJimmy FallonCharlie GrandyAmy OzolsStarsAnthony AndersonJesse BradfordZach CreggerThree 30-something dads struggle as parents because they are still children at heart.
- CreatorBlake AndersonAdam DevineAnders HolmStarsBlake AndersonAdam DevineAnders HolmA single-camera comedy featuring three friends who work together as telemarketers from 9 to 5, and live together from 5 to 9.
- CreatorElizabeth KrugerCraig ShapiroStarsCallie ThorneScott CohenMehcad BrooksA psychotherapist's private life comes apart at the seams when she discovers that her husband is cheating on her. Dr. Dani Santino throws herself fully into her work and soon becomes the most sought-after therapist for celebrity clients.
- CreatorWhitney CummingsStarsWhitney CummingsChris D'EliaRhea SeehornA girl, a guy, and their friends are twenty-somethings living in Chicago.
- CreatorDana FoxStarsDakota JohnsonNat FaxonLucy PunchA free-spirited young guy moves in with his tightly-wound Type-A sister under the guise of being his niece's caregiver.
- CreatorTracy GambleStarsKatey SagalKaley CuocoAmy DavidsonThe Hennessy clan -- mother Cate, daughters Bridget and Kerry, and son Rory -- look to one another for guidance and support after the death of Paul, the family patriarch. Cate's parents lend a hand.
- CreatorTracy NewmanJonathan StarkStarsJim BelushiCourtney Thorne-SmithLarry Joe CampbellA television show centered around a macho everyman, his loving wife, and their three precocious children.