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- CreatorChris BrunoDavid Howard LeeStarsAnna KendrickZac EfronJillian BellA group of friends living at the dawn of human civilization are the first to discover necessities like fire and the wheel. We'll watch as they stumble onto humanity's best, and worst, innovations. Art. Alcohol. Fashion. Racism. Small talk. And, much to their confusion, monogamy.
- CreatorRobert BohnNate MiltonStarsColin MochrieKeith DavidNicole SullivanNo one seems to know why Dusty Craters, a dilapidated nursing home, is floating through space carrying a colorful assortment of grumpy old folks under the care of an evil goat doctor. But then again nothing seems to make sense in a world where a talking two-dollar bill lives in a Cracker Jack box and a three-eyed ape just might be the center of the universe. Best friends Roosi and Big Man uncover these mysteries and more as they go on one epic adventure after another in this buddy comedy.
- CreatorRich MagallanesMark PalmerStarsWayne GraysonAllegra ClarkArturo SandovalA magical kitten has the ability to use her powers and transforms into a multicolored butterfly-unicorn hybrid.
- StarsRichard GordonJeff LualdiMelissa HunterThe adventures of a horny pilot and his friend Hamilton who is a koala
- CreatorMark LittleMark SatterthwaiteStarsMark LittleKyle DooleyKayla LoretteBurdened by his "Chosen One" status and backed by a team of specialists he can't relate to, Gary the demon hunter struggles to keep interest in the Earth-saving duty he never asked for and doesn't want.
- CreatorMatt ThompsonStarsRachael HarrisGary Anthony WilliamsMarshall BellFollowing the abduction of Xander Crews (a.k.a. "Awesome X") The Xtacles take up work doing odd jobs for President Stan.
- CreatorMichael OuweleenErik RichterStarsGary ColeStephen ColbertThomas Michael AllenThird-rate superhero Harvey Birdman gets a new lease on life when he becomes a lawyer.
- CreatorMatt MaiellaroDave WillisStarsDave WillisCarey MeansDana SnyderThe misadventures of a milkshake, an order of fries, a meatball, and their retired next door neighbor in the suburbs of New Jersey.
- CreatorAdam ReedMatt ThompsonStarsHarry GozErik EstradaEllis HenicanThe drama of an oft-doomed aquatic colony and its personnel, who hate each other.
- CreatorJim FortierAndy MerrillPete SmithStarsAndy MerrillC. Martin CrokerGeorge LoweFormer 'Space Ghost' villains Brak and Zorak live their lives in sitcom form.
- CreatorTommy BlachaBrendon SmallStarsBrendon SmallTommy BlachaMark HamillThe epic and over-the-top adventures of Dethklok, the world's most successful death metal band.
- CreatorChristopher McCullochStarsChristopher McCullochJames UrbaniakDoc HammerThe bizarre escapades of pseudo-heroic scientist Dr. Rusty Venture, his competent, high-strung bodyguard, and his two overenthusiastic sons.
- CreatorDino StamatopoulosStarsCarolyn LawrenceScott AdsitBritta PhillipsA parody of past religious-geared animated shows starring Orel, an optimistic God-fearing young boy in a world of cynicism.
- CreatorChristy KaracasBen GruberStephen WarbrickStarsDavid WainTeddy CohnChristopher McCullochIn a surreal world, a large maximum security prison, which houses thousands of dangerous inmates is run by an eccentric warden and his equally odd staff.
- CreatorWill CarsolaDave StewartStarsDave StewartKaitlyn RobrockWill CarsolaThe Goodman family lives with their lovable pet dog, Mr. Pickles, a deviant border collie with a secret satanic streak.
- CreatorRoger BlackWaco O'GuinStarsDaniel ToshRoger BlackDavid HermanA group of never-do-well forest rangers are facing the shutdown of their National Park when a new ranger arrives to help transform them and save the park.
- CreatorBill BurrMichael PriceStarsBill BurrLaura DernJustin LongFollow the Murphy family back to the 1970s, when kids roamed wild, beer flowed freely and nothing came between a man and his TV.
- CreatorRoger BlackWaco O'GuinStarsDavid HermanTom KennyKyle KinaneAnimated series about bad cops. Not bad as in corrupt, bad as in under-performing. They aren't first responders, they are the worst responders.
- CreatorDave JeserMatt SilversteinJordan YoungStarsAdam CarollaJess HarnellAbbey McBrideA parody of reality shows cast with spoofs of several famous types of animated characters.
- CreatorJace RichdaleAngus OblongStarsWill FerrellPamela AdlonJean SmartThe misadventures of a goofy family deformed by toxic waste.
- CreatorBill OakleyJosh WeinsteinStarsBrian PosehnNick JamesonWallace LanghamThe misadventures of a group of disparate roommates who live in a hip neighborhood in a major city.
- CreatorEverett PeckGabor CsupoArlene KlaskyStarsJason AlexanderGregg BergerNancy TravisA crass, womanizing duck works as a private eye with his level-headed pig sidekick, all the while raising a family as a single dad.
- CreatorPete WilliamsStarsPete WilliamsJosh A. CaganRob TinklerThe misadventures of a group of childhood friends who keep in touch while attending separate colleges.
- CreatorAl JeanMike ReissStarsJon LovitzNick JamesonMaurice LaMarcheJay Sherman is a New York film critic who has to review films he doesn't like for a living.
- CreatorJonathan KatzTom SnyderStarsJonathan KatzH. Jon BenjaminLaura SilvermanA therapist struggles with problems of his patients, while dealing with the ones in his personal life.