- Played with Argentina U16, U17 and U21 (2004-2009).
- Midfielder for River Plate (Buenos Aires, 2006-2011), Málaga C.F. (Spain, 2011-2013), Granada CF (Spain, 2013-2015), C.F. Pachuca (Mexico, 2014), Quilmes A.C. (Quilmes, 2015), A.E.K. Athens F.C. (Greece, 2015-16) and C.D. Universidad Católica (Chile, since 2016).
- Honours with River Plate: Argentine Primera División (2008 Clausura). Honours with A.E.K. Athens F.C.: Greek Cup (2016). Honours with C.D. Universidad Católica: Chilean Supercup (2016, 2019, 2020); Chilean Primera División (2016 Apertura, 2018, 2019, 2020).
- Won the gold medal with Argentina Olympic Football Team at the 2008 Olympic Games.
- (December 26, 2009) Had a car accident in Buenos Aires Province where his three friends died.
- Father of, with Jenny Scropanich, Lucía Buonanotte (b. April 2011), Santino Buonanotte (b. 2013) and Amelia Buonanotte (b. 26 September 2019).
- Descended to Primera B Nacional with River Plate in 2011.
- Won the "Cóndor de Bronce" award (Best Foreign Athlete) in 2016.
- His father, amateur footballer Mario Buonanotte, died of complications from a stroke on September 5, 2018.
- Named in the Chilean Primera División Team of the Season in 2018.
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