- Midfielder for Estudiantes de La Plata (2005-2007, 2010, 2022-), Bayern München (Germany, 2007-2010), S.S.C. Napoli (Italy, 2010-11), F.C. Metalist Kharkiv (Ukraine, 2011-2014), Atletico Madrid (Spain, 2013-14), Besiktas J.K. (Turkey, 2014-2016), A.C. Milan (Italy, 2016-17), Trabzonspor (Turkey, 2017-2020) and Fenerbahçe SK (Turkey, 2020-2022).
- Played with Argentina U20 in 2003.
- Honours with Estudiantes de La Plata: Argentine Primera División (2006 Apertura). Honours with Bayern München: DFL-Ligapokal (2007); Bundesliga (2007/08); DFB-Pokal (2007/08); DFL-Supercup (2010). Honours with Atletico Madrid: La Liga (2013/14). Honours with Besiktas J.K.: Süper Lig (2015/16). Honours with A.C. Milan: Supercoppa Italiana (2016).
- Scored the 1-1 goal for Estudiantes LP against Boca Juniors during the final match of 2006 Apertura.
- Won the gold medal with Argentina Olympic Football Team at the 2008 Olympic Games.
- 19 appearances for Argentina National Football Team (2005-2013).
- Father of twins Alfonsina and Rufina (b. 2015) with Carolina Alurralde.
- Top assists of the 2015/16 Süper Lig.
- Played well over 200 games at Europe.
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