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- The quirky spin on Conan Doyle's iconic sleuth pitches him as a "high-functioning sociopath" in modern-day London. Assisting him in his investigations: Afghanistan War vet John Watson, who's introduced to Holmes by a mutual acquaintance.
- A crime-solving duo that cracks the NYPD's most impossible cases. Following his fall from grace in London, eccentric Sherlock escapes to New York where his father forces him to live with his worst nightmare - a sober companion, Dr. Watson.
- Detective Sherlock Holmes and his stalwart partner Watson engage in a battle of wits and brawn with a nemesis whose plot is a threat to all of England.
- Detective Sherlock Holmes is on the trail of criminal mastermind Professor Moriarty, who is carrying out a string of random crimes across Europe.
- The plot is unknown at this time.
- Basil, the rodent Sherlock Holmes, investigates the kidnapping of a toy maker and uncovers its link to his archenemy, Professor Ratigan.
- Sherlock Holmes and Dr Watson solve the mysteries of copper beeches, a Greek interpreter, the Norwood builder, a resident patient, the red-headed league, and one final problem.
- An aged, retired Sherlock Holmes deals with dementia, as he tries to remember his final case, and a mysterious woman, whose memory haunts him. He also befriends a fan, the young son of his housekeeper, who wants him to work again.
- A humorous take on Sir Arthur Conan Doyle's classic mysteries featuring Sherlock Holmes and Doctor Watson.
- Holmes and Dr. Watson solve the mysteries of the Disappearance of Lady Frances Carfax, Thor Bridge, Shoscombe Old Place, The Boscombe Valley Mystery, The Illustrious Client and The Creeping Man.
- Garden gnomes, Gnomeo and Juliet recruit renowned detective Sherlock Gnomes to investigate the mysterious disappearance of other garden ornaments.
- Sherlock Holmes and Dr Watson solve the mysteries of the devil's foot, Silver Blaze, Wisteria Lodge and the Bruce-Partington Plans.
- Set in Victorian London, the series follows a gang of troubled street teens who are manipulated into solving crimes for the sinister Doctor Watson and his mysterious business partner, the elusive Sherlock Holmes.
- The younger brother of the consulting detective tries to steal Sherlock's glory by solving an important case assisted by an eccentric Scotland Yard detective and a lovely but suspicious actress.
- When assorted people start having inexplicable delusions that lead to their deaths, a teenage Sherlock Holmes decides to investigate.
- When a bored Holmes eagerly takes the case of Gabrielle Valladon after an attempt on her life, the search for her missing husband leads to Loch Ness and the legendary monster.
- A drunken Sherlock Holmes is really just a cover for the real detective, Dr. Watson.
- When a nobleman is threatened by a family curse on his newly inherited estate, detective Sherlock Holmes is hired to investigate.
- Sherlock Holmes and Dr. John H. Watson join the hunt for the notorious serial killer, Jack the Ripper.
- Sherlock Holmes and Dr Watson investigate the legend of a supernatural hound, a beast that may be stalking a young heir on the fog-shrouded moorland that makes up his estate.
- The adventures of master detective Sherlock Holmes as he and his assistant, Dr. Watson--and, somewhat reluctantly, the bumbling Inspector Lestrade--battle criminals in London.
- When the latest heir to the Baskerville estate seems to be threatened by a family curse, only the master detective, Sherlock Holmes, can find out the truth.
- To treat his friend's cocaine induced delusions, Watson lures Sherlock Holmes to Sigmund Freud.
- Sherlock Holmes sets out to discover why a trio of murderous villains, including a dangerously attractive female, are desperate to obtain three unassuming and inexpensive little music boxes.
- The master sleuth hunts his archenemy, Professor Moriarty, who is planning the crime of the century.