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- Using a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- When strange seeds drift to earth from space, mysterious pods begin to grow and invade San Francisco, replicating the city's residents one body at a time.
- Young Blade Runner K's discovery of a long-buried secret leads him to track down former Blade Runner Rick Deckard, who's been missing for thirty years.
- A pragmatic paleontologist touring an almost complete theme park on an island in Central America is tasked with protecting a couple of kids after a power failure causes the park's cloned dinosaurs to run loose.
- An endocrinologist in a dysfunctional marriage with an aging, alcoholic wife journeys to Africa seeking a drug that will restore youth.
- With Spider-Man's identity now revealed, Peter asks Doctor Strange for help. When a spell goes wrong, dangerous foes from other worlds start to appear, forcing Peter to discover what it truly means to be Spider-Man.
- A young American studying in Paris in 1968 strikes up a friendship with a French brother and sister. Set against the background of the '68 Paris student riots.
- After being bitten by a genetically-modified spider, a shy teenager gains spider-like abilities that he uses to fight injustice as a masked superhero and face a vengeful enemy.
- A blade runner must pursue and terminate four replicants who stole a ship in space and have returned to Earth to find their creator.
- Following clues to the origin of mankind, a team finds a structure on a distant moon, but they soon realize they are not alone.
- Four teenagers are sucked into a magical video game, and the only way they can escape is to work together to finish the game.
- Dr. Richard Kimble, unjustly accused of murdering his wife, must find the real killer while being the target of a nationwide manhunt led by a seasoned U.S. Marshal.
- Security guard David Dunn uses his supernatural abilities to track Kevin Wendell Crumb, a disturbed man who has twenty-four personalities.
- A biologist signs up for a dangerous, secret expedition into a mysterious zone where the laws of nature don't apply.
- A father and son, both coroners, are pulled into a complex mystery while attempting to identify the cause of death of a young woman who was apparently harboring dark secrets.
- The X-Men send Wolverine to the past in a desperate effort to change history and prevent an event that results in doom for both humans and mutants.
- When a pilot crashes and tells of conflict in the outside world, Diana, an Amazonian warrior in training, leaves home to fight a war, discovering her full powers and true destiny.
- A family man is drafted to fight in a future war where the fate of humanity relies on his ability to confront the past.
- A strange black entity from another world bonds with Peter Parker and causes inner turmoil as he contends with new villains, temptations, and revenge.
- A team of scientists aboard the International Space Station discover a rapidly evolving life form that caused extinction on Mars and now threatens all life on Earth.
- An immortal Scottish swordsman must confront the last of his immortal opponents, a murderously brutal barbarian who lusts for the fabled "Prize".
- A half-vampire, half-mortal man becomes a protector of the mortal race, while slaying evil vampires.
- A man struggles with memories of his past, which include a wife he cannot remember and a nightmarish world no one else ever seems to wake up from.
- A covert team of immortal mercenaries is suddenly exposed and must now fight to keep their identity a secret just as an unexpected new member is discovered.
- A genetically inferior man assumes the identity of a superior one in order to pursue his lifelong dream of space travel.