According to ScrewAttack, the worst video game villains are: Brentalfloss picks Dr. Wily from the "Mega Man" series, James picks Wart from "Super Mario Bros. 2", and Ben and Nick pick Lysandre from "Pokemon X and Y".
Not all power-ups are helpful, and this list proves it. DJ Cutman picks the poison mushroom in the Japanese "Super Mario Bros. 2", Pat picks the frog suit in "Super Mario Bros. 3", and Chad picks the guitar in "Chester Cheetah's Too Cool to Fool".
ScrewAttack lists three game controllers with serious design flaws: The Sega Dreamcast, the unofficial SuperPad 64 for Nintendo 64, and motion controls in general.